Alzheimer’s Disease

Alzheimer’s Disease (AD) is the most common form of dementia. Alzheimer’s disease is a progressive disease that leads to the worsening of cognitive function over time. Tissue Solutions can provide ethically sourced ready to ship inventory of brain tissue. Please contact us to discuss your project requirements or request a quote today.


We can provide Alzheimer’s disease tissue with the following criteria and specifications:


Tissue Types Dissection of specific brain regions including; Cortex, Cerebellum, Hippocampus, Frontal Lobe, Pituitary Gland.

Tissue available from any brain region and also some neural tissue samples.

Braak Stage Braak stage 0 – without any neurofibrillary changes of Alzheimer’s disease type.

Braak Stage 1 – Braak stage 1 is the point at which tau protein starts to clump into tau tangles.

Braak Stage 2 – Tau tangles have accumulated further and have caused some neurons to burst apart and die.

Braak Stage 3 – Tau tangles and neuronal death have likely caused some memory impairment.

Braak Stage 4 – Tau tangles are beginning to form in the outer layers of the cerebral cortex.

Braak Stage 5 – Tau tangles have caused extensive neuronal death, giving rise to severe memory and cognitive impairment.

Braak Stage 6 – Tau tangles have formed extensively throughout the brain and have caused extensive neuronal death
Clinical Data Standard Demographics, Clinical Diagnosis Confirmation from a board-certified Neuropathologist. Specific pathology features such as tau pathology, Neurofibrillary tangles, and Lewy bodies, Braaks confirmation, Medical History, Cause of Death, Serology Results.
Associated Samples* Normal control donors (age and sex matched), CSF, Plasma/Serum, PBMCs.


*Available upon request